{"product_id":"wnt3a-monoclonal-antibody-mb66610","title":"WNT3A Monoclonal Antibody-MB66610","description":"\u003cp\u003eWNT3A Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66610-50, MB66610-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P56704\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF\/LEF family.Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity).Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro).A palmitoylation site was proposed at Cys-77, but it was later shown that this cysteine is engaged in a disulfide bond.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was purified by immunogen affinity chromatography.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of WNT3A protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of WNT3A expression in MCF7 (A), ZR751 (B), MDAMB468 (C), T47D (D) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Protein Wnt-3a\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant Wnt3a protein fragments expressed in E.coli.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906365395123,"sku":"MB66610-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906365427891,"sku":"MB66610-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f2d8517a-e28a-46d2-9820-195a35cf2369.jpg?v=1702918758","url":"https:\/\/afsbio.com\/products\/wnt3a-monoclonal-antibody-mb66610","provider":"AFSBio Inc.","version":"1.0","type":"link"}