{"product_id":"xiap-monoclonal-antibody-bt-mca3866","title":"XIAP Monoclonal Antibody - BT-MCA3866","description":"\u003cp\u003eXIAP Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3866-50, BT-MCA3866-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: XIAP\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4C12G10\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: XIAP\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human XIAP (AA: 1-268) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 56.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P98170\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: API3, ILP1, MIHA, XLP2, BIRC4, IAP-3, hIAP3, hIAP-3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 331\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238413983923,"sku":"BT-MCA3866-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238414016691,"sku":"BT-MCA3866-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_85d82d08-e2d1-4aac-8e9e-901dfaa93a18.png?v=1769380332","url":"https:\/\/afsbio.com\/products\/xiap-monoclonal-antibody-bt-mca3866","provider":"AFSBio Inc.","version":"1.0","type":"link"}