{"product_id":"xpc-monoclonal-antibody-bt-mca2771","title":"XPC Monoclonal Antibody - BT-MCA2771","description":"\u003cp\u003eXPC Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2771-50, BT-MCA2771-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: XPC\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5F4D3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: XPC\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human XPC (AA: 32-133) expressed in mammalian.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 106kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q01831\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: XP3, RAD4, XPCC, p125\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7508\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238506750131,"sku":"BT-MCA2771-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238506782899,"sku":"BT-MCA2771-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2d47e10a-84dc-421a-85f1-6dcad41f46ac.png?v=1769381966","url":"https:\/\/afsbio.com\/products\/xpc-monoclonal-antibody-bt-mca2771","provider":"AFSBio Inc.","version":"1.0","type":"link"}