{"product_id":"xrcc1-rabbit-pab-es3713","title":"XRCC1 rabbit pAb - ES3713","description":"\u003cp\u003eXRCC1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3713-50, ES3713-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 70kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7515\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P18887\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Moves from the nucleoli to the global nuclear chromatin upon DNA damage.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202150654131,"sku":"ES3713-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202150686899,"sku":"ES3713-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_8e835566-4e95-4f80-93df-5e5b23c0a9aa.png?v=1767123081","url":"https:\/\/afsbio.com\/products\/xrcc1-rabbit-pab-es3713","provider":"AFSBio Inc.","version":"1.0","type":"link"}