{"product_id":"xrcc3-polyclonal-antibody-bt-ap09626","title":"XRCC3 Polyclonal Antibody - BT-AP09626","description":"\u003cp\u003eXRCC3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09626-20, BT-AP09626-50, BT-AP09626-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: XRCC3 encodes a member of the RecA\/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: XRCC3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: XRCC3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 37850\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O43542; Mouse: Q9CXE6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: XRCC3; DNA repair protein XRCC3; X-ray repair cross-complementing protein 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7517\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239989731507,"sku":"BT-AP09626-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239989764275,"sku":"BT-AP09626-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239989797043,"sku":"BT-AP09626-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d7629542-a0a9-4769-b942-fb7147b8f0f8.png?v=1769401820","url":"https:\/\/afsbio.com\/products\/xrcc3-polyclonal-antibody-bt-ap09626","provider":"AFSBio Inc.","version":"1.0","type":"link"}