{"product_id":"xrcc4-monoclonal-antibody-5c10-bt-mca0081","title":"XRCC4 Monoclonal Antibody (5C10) - BT-MCA0081","description":"\u003cp\u003eXRCC4 Monoclonal Antibody (5C10)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0081-20, BT-MCA0081-50, BT-MCA0081-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: XRCC4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ICC, IP\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DNA repair protein XRCC4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 38287\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13426; Mouse: Q924T3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7518; Mouse: 108138\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240029970611,"sku":"BT-MCA0081-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240030003379,"sku":"BT-MCA0081-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240030036147,"sku":"BT-MCA0081-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_12a6a21a-3b87-4017-8168-cfe542e52251.png?v=1769402389","url":"https:\/\/afsbio.com\/products\/xrcc4-monoclonal-antibody-5c10-bt-mca0081","provider":"AFSBio Inc.","version":"1.0","type":"link"}