{"product_id":"xrcc4-rabbit-pab-es3716","title":"XRCC4 rabbit pAb - ES3716","description":"\u003cp\u003eXRCC4 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3716-50, ES3716-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human XRCC4. AA range:261-310\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 40kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7518\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q13426\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Chromosome. Localizes to site of double-strand breaks.; [Protein XRCC4, C-terminus]: Cytoplasm. Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202150850739,"sku":"ES3716-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202150883507,"sku":"ES3716-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_2fe05a5e-75a7-44d0-bfd1-e34b281b2d78.png?v=1767123085","url":"https:\/\/afsbio.com\/products\/xrcc4-rabbit-pab-es3716","provider":"AFSBio Inc.","version":"1.0","type":"link"}