{"product_id":"xrcc5-monoclonal-antibody-bt-mca2525","title":"XRCC5 Monoclonal Antibody - BT-MCA2525","description":"\u003cp\u003eXRCC5 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2525-50, BT-MCA2525-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: XRCC5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5C5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: XRCC5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human XRCC5 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 86kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P13010\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: KU80, KUB2, Ku86, NFIV, KARP1, KARP-1, FLJ39089\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7520\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238601187507,"sku":"BT-MCA2525-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238601220275,"sku":"BT-MCA2525-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_46e70284-f47c-499a-b011-631b4724a9c7.png?v=1769382956","url":"https:\/\/afsbio.com\/products\/xrcc5-monoclonal-antibody-bt-mca2525","provider":"AFSBio Inc.","version":"1.0","type":"link"}