{"product_id":"xrcc6-monoclonal-antibody-bt-mca2092","title":"XRCC6 Monoclonal Antibody - BT-MCA2092","description":"\u003cp\u003eXRCC6 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2092-50, BT-MCA2092-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The p70\/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: XRCC6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 7A9E7\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: XRCC6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 69.8kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P12956\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ML8, KU70, TLAA, CTC75, CTCBF, G22P1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2547\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238556426419,"sku":"BT-MCA2092-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238556459187,"sku":"BT-MCA2092-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b7ad53e5-59c8-435c-ac7e-af31f44dfa05.png?v=1769382531","url":"https:\/\/afsbio.com\/products\/xrcc6-monoclonal-antibody-bt-mca2092","provider":"AFSBio Inc.","version":"1.0","type":"link"}