{"product_id":"yb-1-polyclonal-antibody-ra36258","title":"YB-1 Polyclonal Antibody - RA36258","description":"\u003cp\u003eYB-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA36258-50, RA36258-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Y-box binding protein 1 (YBX1) Homo sapiens This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF (paraffin section), ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: YBX1, NSEP1, YB1, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, CBF-A, DNA-binding protein B, DBPB, Enhancer factor I subunit A, EFI-A, Y-box transcription factor, Y-box-binding protein 1, YB-\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC-p: 100-300.Western Blot: 1\/500 - 1\/2000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 36\u003c\/p\u003e\n\n\u003cp\u003eProtein Molecular Weight (kDa): 36\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 4904\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: P67809\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50μL","offer_id":45122486698163,"sku":"RA36258-50","price":360.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122486730931,"sku":"RA36258-100","price":480.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Reed_Product2.png?v=1787773941","url":"https:\/\/afsbio.com\/products\/yb-1-polyclonal-antibody-ra36258","provider":"AFSBio Inc.","version":"1.0","type":"link"}