{"product_id":"yeats2-polyclonal-antibody-bs5668","title":"YEATS2 Polyclonal Antibody-BS5668","description":"\u003cp\u003eYEATS2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS5668-50, BS5668-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: YEATS domain-containing protein 2; YETS2; KIAA1197\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9ULM3\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The YEATS domain-containing protein 2 (YEATS2) is a nuclear protein that is phosphorylated upon DNA damage by ATM or ATR and contains 1 YEATS domain. The gene encoding YEATS2 resides on chromosome 3, which contains about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: YEATS2 polyclonal antibody detects endogenous levels of YEATS2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 150 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of YEATS2 pAb at 1:500 dilution\u003cbr\u003e\nLane 1: A2780 whole cell lysate(40ug)\u003cbr\u003e\nLane 2: MCF-7 whole cell lysate(40ug)\u003cbr\u003e\nLane 3: SK-OVCAR3 whole cell lysate(40ug)\u003cbr\u003e\nLane 4: HEK293T whole cell lysate(40ug)\u003cbr\u003e\nLane 5: A549 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 393-438 of Human YEATS2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911810814131,"sku":"BS5668-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911810846899,"sku":"BS5668-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_865be50c-f573-4f53-bafc-84958782d207.jpg?v=1703179746","url":"https:\/\/afsbio.com\/products\/yeats2-polyclonal-antibody-bs5668","provider":"AFSBio Inc.","version":"1.0","type":"link"}