{"product_id":"zbtb48-polyclonal-antibody-bs8896","title":"ZBTB48 Polyclonal Antibody - BS8896","description":"\u003cp\u003eZBTB48 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS8896-50, BS8896-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Telomere-binding protein that acts as a regμlator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regμlator of telomere length by initiating telomere trimming, a process that prevents the accumμlation of aberrantly long telomeres. Also acts as a transcription regμlator that binds to promoter regions. Regμlates expression of a small subset of genes, including MTFP1. Regμlates expression the J and\/or S elements in MHC II promoter. Acts as a negative regμlator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ZBTB48, HKR3, TZAP, ZNF855, pp9964\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human ZBTB48(NP_005332.1).\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB, 1:500 - 1:2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 77kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P10074\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45940842692787,"sku":"BS8896-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45940842725555,"sku":"BS8896-100","price":582.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_d8474db2-20f3-4b2c-92df-0d7099582232.jpg?v=1788363543","url":"https:\/\/afsbio.com\/products\/zbtb48-polyclonal-antibody-bs8896","provider":"AFSBio Inc.","version":"1.0","type":"link"}