{"product_id":"zfpm1-polyclonal-antibody-e-ab-91990","title":"ZFPM1 Polyclonal Antibody - E-AB-91990","description":"\u003cp\u003eZFPM1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91990-60, E-AB-91990-120, E-AB-91990-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ZFPM1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: FOG; FOG1; ZNF408; ZNF89A; ZC2HC11A; ZFPM1\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q8IX07\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2\/FOG2 (By similarity.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human ZFPM1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 104kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 105KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148830015667,"sku":"E-AB-91990-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148830048435,"sku":"E-AB-91990-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148830081203,"sku":"E-AB-91990-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_806013db-f073-4a6e-bd22-f0f93301409c.png?v=1710330874","url":"https:\/\/afsbio.com\/products\/zfpm1-polyclonal-antibody-e-ab-91990","provider":"AFSBio Inc.","version":"1.0","type":"link"}