{"product_id":"znf281-polyclonal-antibody-e-ab-90442","title":"ZNF281 Polyclonal Antibody - E-AB-90442","description":"\u003cp\u003eZNF281 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-90442-60, E-AB-90442-120, E-AB-90442-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ZNF281\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ZNF281; ZBP-99; ZNP-99\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9Y2X9\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human ZNF281\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:3000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 93kDa\/96kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 110kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146554933427,"sku":"E-AB-90442-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146554966195,"sku":"E-AB-90442-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146554998963,"sku":"E-AB-90442-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f6b2d704-2924-4893-898b-ce0f6d57fe68.png?v=1710297292","url":"https:\/\/afsbio.com\/products\/znf281-polyclonal-antibody-e-ab-90442","provider":"AFSBio Inc.","version":"1.0","type":"link"}