{"product_id":"znt-8-polyclonal-antibody-bt-ap09752","title":"ZnT-8 Polyclonal Antibody - BT-AP09752","description":"\u003cp\u003eZnT-8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09752-20, BT-AP09752-50, BT-AP09752-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Zinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SLC30A8\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ZnT-8 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 40729\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8IWU4; Mouse: Q8BGG0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 169026\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239998841011,"sku":"BT-AP09752-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239998873779,"sku":"BT-AP09752-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239998906547,"sku":"BT-AP09752-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c28a45ee-427f-40e6-8dc3-cc8e9df66cb0.png?v=1769401935","url":"https:\/\/afsbio.com\/products\/znt-8-polyclonal-antibody-bt-ap09752","provider":"AFSBio Inc.","version":"1.0","type":"link"}