{"product_id":"zo-1-recombinant-rabbit-monoclonal-antibody-bs46078","title":"ZO-1 Recombinant Rabbit Monoclonal Antibody - BS46078","description":"\u003cp\u003eZO-1 Recombinant Rabbit mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS46078-50, BS46078-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regμlates adherens junctions. Tight junctions regμlate the movement of ions and macromolecμles between endothelial and epithelial cells. The mμltidomain structure of this scaffold protein, including a postsynaptic density 95\/disc-large\/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing resμlts in mμltiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, ICC\/IF, FC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TJP1, ZO1, Tight junction protein ZO-1, Tight junction protein 1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human ZO-1\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC: 1:200-1:500 ICC\/IF: 1:100 FC: 1:50\u003c\/p\u003e\n\n\u003cp\u003ePurification: Affinity Purification\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 195 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q07157\u003c\/p\u003e\n\n\u003cp\u003eProduct: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45937412767923,"sku":"BS46078-50","price":424.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45937412800691,"sku":"BS46078-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/zo-1-recombinant-rabbit-monoclonal-antibody-bs46078","provider":"AFSBio Inc.","version":"1.0","type":"link"}