HIF1β/ARNT Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16990-20, A16990-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 87kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 405
SWISS: P27540
Alternate Names: HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta; HIF1β/ARNT
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Nuclear Receptor Signaling, Cancer, Invasion and Metastasis, Signal Transduction, mTOR Signaling Pathway, Endocrine Metabolism, Nucleotide metabolism, Cardiovascular, Angiogenesis, Hypoxia.
NCBI Alias: ARNT
Research Use Only