Product Description

TIF1α (Q1034) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2449-50, BS2449-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O15164

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: The protein mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains (a RING, a B box type 1 and a B box type 2) and a coiled coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of TIF1α (Q1034) pAb in paraffin-embedded human brain tissue.

Bioworld Molecular Weight: ~ 117 kDa

Specificity: TIF1α (Q1034) polyclonal antibody detects endogenous levels of TIF1α protein.

Alternative Name: Transcription intermediary factor 1-alpha; TIF1-alpha; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; Tripartite motif-containing protein 24; TRIM24; RNF82; TIF1; TIF1A

Immunogen: Synthetic peptide, corresponding to amino acids 1011-1060 of Human TIF1α.

Conjugate: Unconjugated

Modification: Unmodified