Tropomyosin α Polyclonal Antibody - RA35572

Tropomyosin α Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35572-50, RA35572-100

Citations, Manuals and MSDS Available upon request.

Background: tropomyosin 1 (alpha) (TPM1) Homo sapiens This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000, ELISA 1:10000-20000

Alternative Names: Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 7168

Protein MW (KDa): 38

SWISS: P09493

Source: Rabbit

Research Use Only