Product Description

3HAO Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30917-50, RA30917-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: 3-hydroxyanthranilate 3, 4-dioxygenase (HAAO) Homo sapiens 3-Hydroxyanthranilate 3, 4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 31

Protein Molecular Weight (kDa): 31

Storage: -20°C/1 year

Human Gene ID: 23498

Human SwissProt Number: P46952

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only