ABCA1 Monoclonal Antibody - BT-MCA3682

ABCA1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3682-50, BT-MCA3682-100

Citations, Manuals and MSDS Available upon request.

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction

Target Protein: ABCA1

Applications: ICC, FCM

Clonality: Monoclonal

Clone ID: 6B7A11

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: ABCA1

Immunogen: Purified recombinant fragment of human ABCA1 (AA: 2081-2261) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 254 kDa

UniProt Accession: O95477

Synonyms: TGD, ABC1, CERP, ABC-1, HDLDT1, HPALP1, HDLCQTL13

GeneID: 19

Research Use Only