ABCA1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA20629-50, RA20629-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: ATP binding cassette subfamily A member 1 (ABCA1) Homo sapiens The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008], Reactivity: Human, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 248 Protein Molecular Weight (kDa): 248 Storage: -20°C/1 year Human Gene ID: 19 Human SwissProt Number: O95477 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only