ABCG2 Monoclonal Antibody - BT-MCA0123

ABCG2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0123-50, BT-MCA0123-100

Citations, Manuals and MSDS Available upon request.

Background: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cancer; Signal transduction; Metabolism; Stem cells; Tags and; cell markers

Target Protein: ABCG2

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Reactivity: Human,Mouse,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: ATP-binding cassette sub-family G member 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9UNQ0; Mouse: Q7TMS5

Synonyms: ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD antigen CD338

GeneID: Human: 9429; Mouse: 26357

Research Use Only