ABCG5 Monoclonal Antibody - BT-MCA2910

ABCG5 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2910-50, BT-MCA2910-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.

Research Areas: Cancer, Metabolism, Signal transduction, Cardiovascular

Target Protein: ABCG5

Applications: WB, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1B5D8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ABCG5

Immunogen: Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 72.5kDa

UniProt Accession: Q9H222

Synonyms: STSL

GeneID: 64240

Research Use Only