ABflo® 488 Rabbit anti-Human CD140b/PDGFRβ Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24222-100, A24222-200, A24222-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 37kDa/123kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 5159
SWISS: P09619
Alternate Names: PDGFRB; CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT; platelet-derived growth factor receptor beta
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology and Developmental Biology, Growth factor, Immunology and Inflammation, CD markers, Cardiovascular, Angiogenesis
NCBI Alias: PDGFRB
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC59957
Research Use Only