ABflo® 488 Rabbit anti-Human CD215/IL-15R alpha Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A22582-100, A22582-200, A22582-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 28kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 3601
SWISS: Q13261
Alternate Names: CD215
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Endocrine and metabolic diseases, Obesity, Immunology Inflammation, CDs
NCBI Alias: IL15RA Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC55696
Research Use Only