ABflo® 488 Rabbit anti-Human CD305/LAIR1 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A23975-100, A23975-200, A23975-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 23kDa/29kDa/31kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 3903
SWISS: Q6GTX8
Alternate Names: LAIR1; CD305; LAIR-1; leukocyte-associated immunoglobulin-like receptor 1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology and Inflammation, CD markers
NCBI Alias: LAIR1
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC61434
Research Use Only