ABflo® 488 Rabbit anti-Human Cytokeratin 18 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27943-100, A27943-200, A27943-500
Citations, Manuals and MSDS Available upon request.
Background: Keratins (also known as cytokeratins) are intermediate filament proteins primarily expressed in epithelial cells. A keratin heterodimer, composed of one acidic keratin (or type I keratin, keratins 9 to 23) and one basic/neutral keratin (or type II keratin, keratins 1 to 8), polymerizes to form filaments. The tissue-specific and differentiation-specific expression patterns of keratin isoforms enable them to serve as valuable biomarkers. Studies have confirmed that mutations in keratin genes are associated with dermatological disorders, liver and pancreatic diseases, and inflammatory bowel diseases.
Category: Monoclonal Antibodies
Application: FC (intra)
Cross Reactivity: Human
Protein Weight: 48kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 3875
SWISS: P05783
Alternate Names: K18; CK-18; CYK18
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume
Research Areas: Epithelial Cell Apoptosis Biomarkers, Liver Disease Monitoring, Cancer Diagnostic Applications
NCBI Alias: KRT18
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC75640
Research Use Only