ABflo® 488 Rabbit anti-Human Desmoglein 3/PVA Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A26590-100, A26590-200, A26590-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 108kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 1830
SWISS: P32926
Alternate Names: PVA; ABOLM; CDHF6
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cadherins, Cytoskeleton, Extracellular Matrix
NCBI Alias: DSG3
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC69331
Research Use Only