ABflo® 488 Rabbit anti-Human GSK3β Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A26725-100, A26725-200, A26725-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
Category: Monoclonal Antibodies
Application: FC (intra)
Cross Reactivity: Human
Protein Weight: 47kDa Immunogen: Synthetic peptide.
Species: Human
GeneID: 2932
SWISS: P49841
Alternate Names: GSK3B; glycogen synthase kinase-3 beta; GSK3β
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume
Research Areas: Epigenetics Nuclear Signaling, Translation Control, Regulation of eIF4 and p70 S6 Kinase, Protein phosphorylation, Cancer, Signal Transduction, Kinase, Serine threonine kinases, PI3K-Akt Signaling Pathway, mTOR Signaling Pathway, ErbB-HER Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, Cell Cycle, Centrosome, Cell Cycle Control-G1 S Checkpoint, Cell Adhesion, Microtubules, Wnt ??-Catenin Signaling Pathway, ESC Pluripotency and Differentiation, Endocrine Metabolism, Carbohydrate metabolism, Insulin Receptor Signaling Pathway, Endocrine and metabolic diseases, Diabetes, Immunology Inflammation, B Cell Receptor Signaling Pathway, NF-kB Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Neurodegenerative Diseases Markers, Other Neurological disorders, Stem Cells, Cardiovascular, Heart, Hypertrophy
NCBI Alias: GSK3B
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC70827
Research Use Only