ABflo® 594 Rabbit anti-Human EGFR Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24267-100, A24267-200, A24267-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Category: Monoclonal Antibodies
Application: IF/ICC, FC
Cross Reactivity: Human
Protein Weight: 44kDa/69kDa/77kDa/134kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 1956
SWISS: P00533
Alternate Names: EGFR; ERBB; ERBB1; HER1; NISBD2; PIG61; mENA; epidermal growth factor receptor
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: IF/ICC,1:50 - 1:200|FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Tumor biomarkers, Signal Transduction, G protein signaling, Kinase, Tyrosine kinases, Phospholipase Signaling Pathway, ErbB-HER Signaling Pathway, Cell Biology and Developmental Biology, Growth factor, EGF, Immunology and Inflammation, IL-6 Receptor Signaling Pathway, Cardiovascular, Angiogenesis
NCBI Alias: EGFR
Modifications: Unmodified
Conjugate: ABflo® 594. Ex:588nm. Em:604nm.
Clone Number Info: ARC61443
Research Use Only