ABHD12 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A17678-20, A17678-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 45kDa
Observed Molecular Weight: 45kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 26090
SWISS: Q8N2K0
Alternate Names: PHARC; ABHD12A; BEM46L2; hABHD12; C20orf22; dJ965G21.2; ABHD12
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: ABHD12
Research Use Only