ABHD12 Rabbit pAb - A17678

ABHD12 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A17678-20, A17678-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Rat

Protein Weight: 45kDa

Observed Molecular Weight: 45kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 26090

SWISS: Q8N2K0

Alternate Names: PHARC; ABHD12A; BEM46L2; hABHD12; C20orf22; dJ965G21.2; ABHD12

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

NCBI Alias: ABHD12

Research Use Only