ACE1 Monoclonal Antibody - BT-MCA0124

ACE1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0124-50, BT-MCA0124-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Research Areas: Cancer; Signal transduction; Metabolism; Stem cells; Cardiovascular; Cell biology

Target Protein: ACE

Applications: WB

Reactivity: Human,Mouse,Rat,Bovine

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Angiotensin-converting enzyme

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P12821; Mouse: P09470; Rat: P47820

Synonyms: ACE; DCP; DCP1; Angiotensin-converting enzyme; ACE; Dipeptidyl carboxypeptidase I; Kininase II; CD antigen CD143

GeneID: Human: 1636; Mouse: 11421; Rat: 24310

Research Use Only