Product Description

ACHA4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30974-50, RA30974-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: cholinergic receptor nicotinic alpha 4 subunit (CHRNA4) Homo sapiens This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 68

Protein Molecular Weight (kDa): 68

Storage: -20°C/1 year

Human Gene ID: 1137

Human SwissProt Number: P43681

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only