ACPL2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS65458-50, BS65458-100
Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Swiss-Prot: Q8TE99
Host: Rabbit
Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep
Applications: IHC-P
All Applications: IHC-P=1:100-500
Background: ACLP2 (acid phosphatase-like 2), also known as UNQ370 or PRO706, is a 480 amino acid secreted protein that functions to catalyze the H2O-dependent conversion of a phosphate monoester to an alcohol and a phosphate. Expressed as two alternatively spliced isoforms, ACPL2 is encoded by a gene that maps to chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Purification and Purity: affinity purified by Protein A
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ACPL2 Polyclonal Antibody detects endogenous levels of ACPL2 protein.
Bioworld Molecular Weight: 62 kD
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ACPL2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C., Paraformaldehyde-fixed, paraffin embedded (rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ACPL2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C., Paraformaldehyde-fixed, paraffin embedded (rat lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ACPL2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C.
Alternative Name: acid phosphatase-like 2; Acid phosphatase-like protein 2; acpl2; ACPL2_HUMAN; EC=3.1.3.2.
Immunogen: KLH conjugated synthetic peptide derived from human ACPL2:51-150/480
Conjugate: Unconjugated
Modification: Unmodified