Product Description

Actived-Caspase-9 p35 (D315) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7070-50, BS7070-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimμlation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resμlting in cleavage at Asp315 and producing a p35 subunit.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: APAF 3, APAF-3, APAF3, Apoptosis related cysteine peptidase, Apoptotic protease activating factor 3, Apoptotic protease Mch 6, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP 9, CASP-9, CASP9, Caspase 9 apoptosis related cysteine peptidase, Caspase 9 Dominant Negative, Caspase 9c, Caspase-9, Caspase9, ICE LAP6, ICE like apoptotic protease 6, ICE-LAP6, ICE-like apoptotic protease 6, MCH6, RNCASP9

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human Caspase 9.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Actived-Caspase-9 p35 (D315) polyclonal antibody detects detects endogenous levels of the 35 kDa large fragment of caspase-9 following cleavage at aspartic acid 315.

Molecular Weight: ~ 35 kDa

Pathway: Regμlation of Apoptosis, Inhibition of Apoptosis, Mitochondrial Control of Apoptosis, Death Receptor Signaling,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P55211

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only