ACVR1B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5453-20, A5453-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 57kDa
Observed Molecular Weight: 49kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 91
SWISS: P36896
Alternate Names: ALK4; SKR2; ACTRIB; ACVRLK4; ACVR1B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Cytoskeleton, Microfilaments, Stem Cells.
NCBI Alias: ACVR1B
Research Use Only