Product Description

Adducin α/β (phospho-S726/713) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS4005-50, BS4005-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodμlin and is a substrate for protein kinases A and C. Alternative splicing resμlts in mμltiple variants encoding distinct isoforms, however, not all variants have been fμlly described.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA, α-Adducin, Adducin1, Adducin-1, α Adducin, Adducin-α, Beta-adducin, Erythrocyte adducin subunit beta, ADD2, ADDB, β-Adducin, Adducin1, Adducin-1, β Adducin, Adducin β, Adducin-β

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human Adducin α around the phosphorylation site of Serine 726.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: p-Adducin α/β (S726/713) polyclonal antibody detects endogenous levels of Adducin α protein only when phosphorylated at Ser726 and Adducin β protein only when phosphorylated at Ser713.

Molecular Weight: ~ 81 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P35611/P35612

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only