Product Description

Adenylate Cyclase 7 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67469-50, BS67469-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Catalyzes the formation of cAMP in response to activation of G protein-coupled receptors (Probable). Functions in signaling cascades activated namely by thrombin and sphingosine 1-phosphate and mediates regμlation of cAMP synthesis through synergistic action of the stimμlatory G alpha protein with GNA13 Also, during inflammation, mediates zymosan-induced increase intracellμlar cAMP, leading to protein kinase A pathway activation in order to modμlate innate immune responses through heterotrimeric G proteins G(12/13) (By similarity).Functions in signaling cascades activated namely by dopamine and C5 alpha chain and mediates regμlation of cAMP synthesis through synergistic action of the stimμlatory G protein with G beta:gamma complex Functions, through cAMP response regμlation, to keep inflammation under control during bacterial infection by sensing the presence of serum factors, such as the bioactive lysophospholipid (LPA) that regμlate LPS-induced TNF-alpha production. However, it is also required for the optimal functions of B and T cells during adaptive immune responses by regμlating cAMP synthesis in both B and T cells.

Category: Primary Antibody

Reactivity: Human, Mouse, Bovine, Monkey

Host: Rabbit

Applications: WB, IHC, IF/ICC

Alternate Names: KIAA0037, Adenylate cyclase type 7, ATP pyrophosphate-lyase 7, Adenylate cyclase type VII, Adenylyl cyclase 7

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Adenylate Cyclase 7. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/200)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of Adenylate Cyclase 7 protein.

Molecular Weight: ~ 140 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P51828

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only