AFP Monoclonal Antibody - BT-MCA2176

AFP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2176-50, BT-MCA2176-100

Citations, Manuals and MSDS Available upon request.

Background: AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Research Areas: Cardiovascular, Cancer

Target Protein: AFP

Applications: WB

Reactivity: Human

Clonality: Monoclonal

Clone ID: 6E6

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: AFP

Immunogen: Purified recombinant fragment of human AFP expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 69kDa

UniProt Accession: P02771

Synonyms: alpha-fetoprotein, FETA, HPAFP

GeneID: 174

Research Use Only