AFP Monoclonal Antibody - BT-MCA4562

AFP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4562-50, BT-MCA4562-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Research Areas: Cardiovascular, Cancer

Target Protein: AFP

Applications: IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2G4H3

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: AFP

Immunogen: Purified recombinant fragment of human AFP (AA: 19-210) expressed in HEK293-6e cells supernatant.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 68.6kDa

UniProt Accession: P02771

Synonyms: AFPD, FETA, HPAFP

GeneID: 174

Research Use Only