AGRN Rabbit pAb - A17320

AGRN Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A17320-20, A17320-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 217kDa

Observed Molecular Weight: 98kDa/217kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 375790

SWISS: O00468

Alternate Names: CMS8; AGRIN; CMSPPD; AGRN

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cell Adhesion, Neuroscience, Cell Type Marker, Neuron marker.

NCBI Alias: AGRN

Research Use Only