AGT Monoclonal Antibody - BT-MCA4379

AGT Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4379-50, BT-MCA4379-100

Citations, Manuals and MSDS Available upon request.

Background: AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Research Areas: Epigenetics and nuclear signaling

Target Protein: AGT

Applications: WB

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1B1

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: AGT

Immunogen: Purified recombinant fragment of human AGT expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 53kDa

UniProt Accession: P01019

Synonyms: ANHU

GeneID: 183

Research Use Only