Akt2 Monoclonal Antibody - BT-MCA0145

Akt2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0145-50, BT-MCA0145-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Research Areas: Cancer; Signal transduction; Metabolism; Cardiovascular

Target Protein: AKT2

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human,Rat,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: RAC-beta serine,threonine-protein kinase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P31751; Mouse: Q60823; Rat: P47197

Synonyms: AKT2; RAC-beta serine; threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta

GeneID: Human: 20825233

Research Use Only