AKT2 Monoclonal Antibody - BT-MCA4701

AKT2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4701-50, BT-MCA4701-100

Citations, Manuals and MSDS Available upon request.

Background: Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.

Research Areas: Signal Transduction, Metabolism

Target Protein: AKT2

Applications: WB, IHC, ICC

Reactivity: Human, Rat, Monkey

Clonality: Monoclonal

Clone ID: 1B6

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: AKT2

Immunogen: Purified recombinant fragment of human AKT2 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 60kDa

UniProt Accession: P31751

Synonyms: PKBB, PRKBB, PKBBETA, RAC-BETA

GeneID: 208

Research Use Only