Product Description

AKT2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-91970-60, E-AB-91970-120, E-AB-91970-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: AKT2

Target Synonym: AKT2; HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat, Monkey

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P31751

Background: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human AKT2

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 51kDa/55kDa

Observed MW: 60kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only