Aldose Reductase Monoclonal Antibody - BT-MCA0151

Aldose Reductase Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0151-50, BT-MCA0151-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Research Areas: Signal transduction; Metabolism

Target Protein: AKR1B1

Applications: WB

Reactivity: Human,Mouse,Dog,Rabbit

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Aldose reductase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P15121; Mouse: P45376; Rat: P07943

Synonyms: AKR1B1; ALDR1; Aldose reductase; AR; Aldehyde reductase; Aldo-keto reductase family 1 member B1

GeneID: Human: 231; Mouse: 11677

Research Use Only