Product Description

ALS2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31071-50, RA31071-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ALS2, alsin Rho guanine nucleotide exchange factor (ALS2) Homo sapiens The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 182

Protein Molecular Weight (kDa): 182

Storage: -20°C/1 year

Human Gene ID: 57679

Human SwissProt Number: Q96Q42

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only