AMACR Monoclonal Antibody - BT-MCA0152

AMACR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0152-50, BT-MCA0152-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Research Areas: Signal transduction; Tags and; cell markers; Metabolism; Cancer; Epigenetics and nuclear signaling

Target Protein: AMACR

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Alpha-methylacyl-CoA racemase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9UHK6; Mouse: O09174

Synonyms: AMACR; Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase

GeneID: Human: 23600; Mouse: 17117

Research Use Only