Product Description

AMGO2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31076-50, RA31076-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas., similarity:Belongs to the immunoglobulin superfamily. AMIGO family., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 6 LRR (leucine-rich) repeats., subcellular location:Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons., subunit:Binds itself as well as AMIGO1 and AMIGO3., tissue specificity:Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 57

Protein Molecular Weight (kDa): 57

Storage: -20°C/1 year

Human Gene ID: 347902

Human SwissProt Number: Q86SJ2

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only